E-ATX Z490 Motherboards + Faster RAM?

Getting PCIe slot issues when assembling high end overclocked PCs with normal ATX motherboards. Are we going to get to choose E-ATX motherboards as well? With SLI support and preferably with at least 3 M.2 slots and enough expansion slots for 2 large GPU's and a PCIe capture card or sound card. Planning an RTX 3080 Ti build for August and hopefully make my first order here then. While I'm sure you'll get the GPU's when possible, I felt I had to ask about the E-ATX motherboards.
 
On the side-note, the MSI MEG Z490 GODLIKE includes a M.2 Xpander-Z Gen-4 PCIe card that allows for another 4 extra M.2 slots. Though I heard it has pretty loud fan cooling.
 
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